The value of neuron-specific enolase in prognostication after cardiac arrest

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Serial measurement of neuron specific enolase improves prognostication in cardiac arrest patients treated with hypothermia: A prospective study

BACKGROUND Neuron specific enolase (NSE) has repeatedly been evaluated for neurological prognostication in patients after cardiac arrest. However, it is unclear whether current guidelines for NSE cutoff levels also apply to cardiac arrest patients treated with hypothermia. Thus, we investigated the prognostic significance of absolute NSE levels and NSE kinetics in cardiac arrest patients treate...

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Neurological prognostication after cardiac arrest

The care of the comatose cardiac arrest patient and his/her relatives in the ICU constitutes a major challenge for intensivists. Out-of-hospital cardiac arrest (OHCA) affects more than 275.000 Europeans yearly; survival rates are disturbingly low and have until recently remained unchanged [1]. During the last several years, significant efforts have been made to improve the quality of prehospita...

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[Serum neuron-specific enolase as a prognostic marker after a cardiac arrest].

BACKGROUND AND OBJECTIVES Cardiac arrest is a state of severe cerebral perfusion deficit. Patients recovering from a cardiopulmonary resuscitation are at great risk of subsequent death or incapacitating neurologic injury, including persistent vegetative state. The early definition of prognosis for these patients has ethical and economic implications. The main purpose of this manuscript was to r...

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Serum neuron-specific enolase as early predictor of outcome after in-hospital cardiac arrest: a cohort study

INTRODUCTION Outcome after cardiac arrest is mostly determined by the degree of hypoxic brain damage. Patients recovering from cardiopulmonary resuscitation are at great risk of subsequent death or severe neurological damage, including persistent vegetative state. The early definition of prognosis for these patients has ethical and economic implications. The main purpose of this study was to in...

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Prognostication after out-of-hospital cardiac arrest, a clinical survey

BACKGROUND Numerous parameters and tests have been proposed for outcome prediction in comatose out-of-hospital cardiac arrest survivors. We conducted a survey of clinical practice of prognostication after therapeutic hypothermia (TH) became common practice in Norway. METHODS By telephone, we interviewed the consultants who were in charge of the 25 ICUs admitting cardiac patients using 6 struc...

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ژورنال

عنوان ژورنال: Resuscitation

سال: 2018

ISSN: 0300-9572

DOI: 10.1016/j.resuscitation.2017.11.061